A Review of the Environmental Safety of the Cry1F Protein

This document provides a comprehensive review of the information and data relevant to the environmental risk assessment of Cry1F, a family of proteins encoded by genes isolated from Bacillus thuringiensis (Bt), and it presents a summary statement about the environmental safety of these proteins when produced in genetically engineered (GE) cotton (Gossypium hirsutum) and maize (Zea mays) plants. All sources of information reviewed herein are publicly available and include dossiers presented to regulatory authorities, decision documents prepared by regulatory authorities, product descriptions prepared by product developers, and peer-reviewed literature.